Tuesday, October 16, 2007

SSRI's for PMS




How effective are selective serotonin reuptake inhibitors (SSRI’s) for the treatment of PMS?

SSRI’s are a class of drugs used in the treatment of depression, anxiety, and personality disorders. Patients can experience many side effects from the use of these medications including weight changes, increase in anxiety, suicidal thoughts, and sexual dysfunction. A study published in the Cochrane Database concluded that there is very good evidence to support the use of selective serotonin reuptake inhibitors in the management of severe PMS. However, withdrawals due to side effects were 2.5 times more likely to occur in the treatment group than in the placebo group.3

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