Tuesday, October 16, 2007

What medical treatments are available for PMS and PMDD?

there are four types of prescription drugs used for PMS/PMDD:

  1. Antidepressants that act on serotonin, including fluoxetine, sertraline, and paroxetine.The FDA has recently ordered makers of several antidepressants to issue black box warnings that patients on these medications should be closely monitored for “clinical worsening, suicidality, or unusual changes in behavior.”
  2. Agents that suppress ovulation, such as danazol, transdermal estradiol patches, and some oral contraceptives. These medications carry risks for serious side effects and can be very expensive.
  3. Other psychotropics to reduce anxiety, such as alprazolam and other anxiolytic benzodiazepines. Since alprazolam has a very short half-life, there is a risk of addiction for patients who are started on this medication.
  4. Spironolactone, a diuretic that is only available by prescription. It has proven effective in reducing premenstrual fluid retention, but doesn’t address the other symptoms of PMS.

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